Search Result

Search Results for " mic 5 "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T7342	BM212		Antibacterial
	BM212 is an antimycobacterial compound.It inhibits the growth of laboratory and clinical isolate M. tuberculosis strains.		Antibacterial
T1154	Rifaximin		DNA/RNA Synthesis , Antibacterial , Antibiotic
	Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting...		DNA/RNA Synthesis , Antibacterial , Antibiotic
T38240	2,6-Dichlorodiphenylamine		Antibacterial
	2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1...		Antibacterial
T62753	MsbA-IN-5
	MsbA-IN-5 (compound 40) is a potent and highly selective inhibitor of MsbA (IC50: 2 nM). MsbA-IN-5 can be used in Gram-negative studies.
T80411	Bactenecin 5
	Bactenecin 5, a bovine antibacterial peptide, exhibits activity against Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae, with minimum inhibitory concentration (MIC) values ranging from 12-25 μg/mL [1]...
T80368	Im5
	Im5, an antimicrobial peptide, exhibits antibacterial activity, with minimum inhibitory concentrations (MIC) of 10 μM for E. coli, 2.5-5 μM for S. aureus, and 0.5-1 μM for B. subtilis, as well as hemolytic activity with ...
T60645	Glutamate-5-kinase-IN-2
	Glutamate-5-kinase-IN-2 (compound 54) exhibits G5K inhibition by promotes conformational changes at the L-glutamate binding site that is a potent glutamate-5-kinase (G5K) inhibitor with an MIC of 4.2 μM. Glutamate-5-kina...
T80400	Peptide 5e
	Peptide 5e, an antimicrobial peptide, exhibits inhibitory activity against E. coli, S. aureus, and C. albicans with respective minimum inhibitory concentration (MIC) values of 30, 5, and 25 μg/mL [1].
T79440	DprE1-IN-5
	DprE1-IN-5 (Compound 10), a potent DprE1 inhibitor, exhibits anti-TB activity with an MIC of 4 μM against the Mtb H37Rv strain and demonstrates antimycobacterial efficacy against drug-resistant strains. Additionally, it ...
T61573	MtTMPK-IN-5
	MtTMPK-IN-5 (compound 17) is a highly effective inhibitor of M. tuberculosis thymidylate kinase (Mtb TMPK), demonstrating remarkable enzyme inhibitory activity with an IC50 value of 34 μM. Additionally, MtTMPK-IN-5 exhib...
T62081	Mt KARI-IN-5
	Mt KARI-IN-5 (compound 6c) was a potent inhibitor of Mycobacterium tuberculosis ketohydrin reductase I (MtbKARI) (Ki: 4.72 μM). Mt KARI-IN-5 exhibited inhibition of MtbH37Rv activity with a MIC value of 1.56 μM, low cyto...
T60693	Glutamate-5-kinase-IN-1
	Glutamate-5-kinase-IN-1 (compound 50) is a potent glutamate-5-kinase (G5K) inhibitor which acts by altering the ATP binding site architecture for enzyme recognition (MIC = 4.1 μM). Glutamate-5-kinase-IN-1 has the potenti...
T75313	Methdilazine
	Methdilazine, an orally active (histamine antagonist) antibiotic, demonstrates the ability to inhibit various mycobacteria with minimum inhibitory concentration (MIC) values ranging from 5-15 μg/mL both in vitro and in v...
T64160	MraY-IN-3
	MraY-IN-3 (12a) is a potent inhibitor of the bacterial translocase MraY (IC50: 140 μM). 46 μg/ml).
T62338	IMPDH2-IN-2
	IMPDH2-IN-2 is a potent inhibitor of inosine 5'-monophosphate dehydrogenase (IMPDH) (Ki,app: 14 μM) and a potential anti-tuberculosis agent. IMPDH2-IN-2 has a moderate antibacterial effect with MIC values of 6.3 and 11 μ...
T39790	LpxC-IN-5
	LpxC-IN-5 is a potent, non-hydroxamate inhibitor of LpxC, which is an enzyme known as UDP-3-O-acyl-N-acetylglucosamine deacetylase. It exhibits an IC50 value of 20 nM. Furthermore, LpxC-IN-5 displays antibacterial activi...
T62305	MtTMPK-IN-2
	MtTMPK-IN-2 (compound 15), a potent inhibitor of Mycobacterium tuberculosis thymidylate kinase (Mt TMPK), demonstrates an IC50 value of 1.1 μM. This compound effectively inhibits Mtb H37Rv with a minimum inhibitory conce...
T62897	MtTMPK-IN-3
	MtTMPK-IN-3 (compound 25) is a potent inhibitor of Mycobacterium tuberculosis thymidylate kinase (MtTMPK) with an IC50 value of 0.12 μM. It also demonstrates inhibitory activity against Mtb H37Rv with a MIC of 12.5 μM an...
T36474	TunR1
	TunR1 is an antibiotic and derivative of tunicamycin .1It is active againstB. subtilis(MIC = 0.3 μg/ml) and increases the efficacy of the β-lactam antibiotics oxacillin , methicillin , and penicillin G againstB. subtilis...
T35978	Benastatin A
	Benastatin A is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2,3It inhibits glutathione S-transferase (GST; Ki= 5 μM for the rat liver enzyme).2Benast...
T32669	Leucomycin a5	Leukomycin A5,Turimycin H4
	Leucomycin a5 is a metabolite from the leucomycin complex, which was originally isolated from S. kitasatoensis. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.04-0.8 µg/ml) but not a...
T36706	Bottromycin A2
	Bottromycin A2is an antibiotic originally isolated fromStreptomyces.1It blocks the binding of aminoacyl-tRNA to the A site of the 50S ribosome, inhibiting protein synthesis.2Bottromycin A2is active against clinical isola...
T36539	Nocardamine
	Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. b...
T35757	Beauvericin A
	Beauvericin A is a cyclodepsipeptide and derivative of beauvericin originally isolated fromB. bassianathat has diverse biological activities.1,2,3It is active againstM. tuberculosis(MIC = 25 μg/ml) andP. falciparum(IC50=...
T38009	Kocurin
	Kocurin is a thiazolyl peptide originally isolated fromK. palustrisand has antibiotic activity.1It is active against methicillin-resistantS. aureus(MRSA; MIC = 0.25 μg/ml), as well asB. subtilisandE. faeciumin a solid ag...
T35453	β-Defensin-4 (human) (trifluoroacetate salt)
	β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at...

Compounds

BM212

T7342

Synonym:

Target: Antibacterial

Rifaximin

T1154

Synonym:

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

2,6-Dichlorodiphenylamine

T38240

Synonym:

Target: Antibacterial

Glutamate-5-kinase-IN-2

Glutamate-5-kinase-IN-1

Synonym: Leukomycin A5,Turimycin H4

β-Defensin-4 (human) (trifluoroacetate salt)

T35453

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T14329	Ascamycin		Nucleoside Antimetabolite/Analog , Others , Antibacterial , Antibiotic
	Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and inhibits Xanthomonas citri, Xanthomonas oryzae and phage w...
TN1291	7,3',4'-Tri-O-methylluteolin	5-Hydroxy-3',4',7-trimethoxyflavone	TNF , COX , Interleukin
	7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC value of 19.0 ug/ml		TNF , COX , Interleukin
T2S1865	Octyl gallate	Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8	Antioxidant , Influenza Virus , Reactive Oxygen Species , Antibacterial , Antifungal , HSV
	1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Octyl Gallate shows antimicrobial activity against H. pylori, ...
TN4098	Gancaonin I		GTPase , Antifection
	Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM.		GTPase , Antifection
T80335	Maximin H3
	Maximin H3, an antimicrobial peptide from Chinese red belly toad Bombina maxima skin secretions, exhibits antimicrobial properties against Escherichia coli ATCC25922, Staphylococcus aureus ATCC2592, Bacillus pyocyaneus C...
T38295	Calpinactam
	Calpinactam is a fungal metabolite originally isolated from M. alpina that has antimycobacterial activity. It is active against M. smegmatis (MIC = 0.78 μg/ml) but not a panel of 13 other bacteria and fungi. Calpinactam ...
T80330	XT-1
	XT-1, an antimicrobial peptide sourced from Xenopus tropicalis skin secretions, exhibits potent activity against S. aureus, E. coli, and C. albicans, with minimum inhibitory concentration (MIC) values of 5, 6, and 50 μM,...
T75560	4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl-
	4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- (compound 2), a quinolone alkaloid extracted from Cnidium, demonstrates activity against methicillin-resistant Staphylococcus aureus (MRSA), exhibiting minimum inhibitor...
T35911	Piliformic Acid
	Piliformic acid is a fungal metabolite that has been found inN. pseudotrichiaand has diverse biological activities.1,2It is cytotoxic to BC-1 human breast cancer cells (IC50= 5 μg/ml).2Piloformic acid is active againstL....
TN4148	Glyasperin C		Tyrosinase , Antifection
	Glyasperin C acts as a partial estrogen antagonist, it shows tyrosinase inhibitory activity (IC (50) = 0.13 +/- 0.01 microg/mL), it could be a promising candidate in the design of skin-whitening agents. Glyasperin C show...		Tyrosinase , Antifection
T36438	Sporogen-AO 1
	Sporogen-AO 1 is a fungal metabolite originally isolated fromA. oryzaethat has diverse biological activities.1,2,3,4,5It inhibits HIV-1 Tat transactivation in a cell-based assay with an IC50value of 15.8 μM.4Sporogen-AO ...
T35752	Xanthoquinodin A1	Xanthoquinodin A1
	Xanthoquinodin A1 is a fungal metabolite that has been found inHumicolaand has diverse biological activities.1,2It inhibitsE. tenellaschizont formation in BHK-21 cells with a minimum effective concentration (MEC) value o...
T35779	Oosporein
	Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectiv...

Natural Products

Ascamycin

T14329

Synonym:

Target: Nucleoside Antimetabolite/Analog, Others, Antibacterial, Antibiotic

7,3',4'-Tri-O-methylluteolin

TN1291

Synonym: 5-Hydroxy-3',4',7-trimethoxyflavone

Target: TNF, COX, Interleukin

Octyl gallate

T2S1865

Synonym: Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8

Target: Antioxidant, Influenza Virus, Reactive Oxygen Species, Antibacterial, Antifungal, HSV

Gancaonin I

TN4098

Synonym:

Target: GTPase, Antifection

4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl-

Target: Tyrosinase, Antifection

Synonym: Xanthoquinodin A1

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01431	L1CAM Protein, Human, Recombinant (His)	Human	HEK293
	L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai...
TMPY-05587	EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d...
TMPK-00811	L1CAM Protein, Mouse, Recombinant (His)	Mouse	HEK293
	L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many huma...
TMPY-01300	EpCAM/TROP1 Protein, Human, Recombinant (His)	Human	HEK293
	Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d...
TMPY-06759	L1CAM Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai...
TMPY-06857	L1CAM Protein, Human, Recombinant (hFc)	Human	HEK293
	L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai...
TMPY-00785	EpCAM/TROP1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d...
TMPY-06849	EpCAM/TROP1 Protein, Human, Recombinant (mFc)	Human	HEK293
	Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d...
TMPY-04953	EpCAM/TROP1 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d...
TMPY-05601	EpCAM/TROP1 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d...
TMPY-05117	EpCAM/TROP1 Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293
	Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d...
TMPK-00680	EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus macaque	HEK293
	Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like r...
TMPK-00207	EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His)	Human	HEK293
	Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like r...
TMPK-00679	EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant	Cynomolgus,Rhesus macaque	HEK293
	Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like r...
TMPK-00206	EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc)	Human	HEK293
	Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like r...
TMPK-00205	EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated	Human	HEK293
	Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like r...
TMPY-05308	CD45 Protein, Human, Recombinant (aa 1-529, His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-00854	ETS1 Protein, Human, Recombinant (His)	Human	E. coli
	ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or ...
TMPY-05498	SR-BI/SCARB1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPY-05387	SLAMF7 Protein, Human, Recombinant (hFc)	Human	HEK293
	SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPY-05547	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293
	SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc)	Human	HEK293
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPK-01363	SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01357	SIRP alpha V5 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...